Chemotherapy combination adds 5 weeks to lung cancer survival
When used in conjunction with chemotherapy, a new treatment has been shown to increase life-span by five weeks among lung cancer patients.
A study released last week indicates that the drug Erbitux, created by ImClone Systems Inc, can both help lung cancer survival and decrease tumor size when used with chemotherapy treatments. The study involved 1,125 patients; overall survival was 11.3 months for patients on the combination therapy, compared with 10.1 months for the group receiving just chemotherapy. Tumors shrunk in 36.3 percent of patients treated with Erbitux, also known as cetuximab, compared with 29.2 percent of patients on chemotherapy alone, according to a statement from the American Society of Clinical Oncology.
Prior to the publication of these promising results, the only non-chemo treatment for lung cancer had been Genentech Inc's Avastin, which combats non-small cell lung cancer.
Erbitux is an antibody already approved for treating colorectal as well as head and neck cancers. It is designed to block a protein called epidermal growth factor, and has so far exhibited only minor side effects. The most common complaint among trial participants was the appearance of an acne-like rash, seen among 10.4% of patients using the combination therapy, compared to .2% of patients receiving only chemo.
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